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ELK Biotechnology

ES3527

SURF-1 Rabbit Polyclonal Antibody

SURF-1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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SURF-1 Rabbit Polyclonal Antibody

Overview

Product name: SURF-1 rabbit pAb
Alternative Names: SURF1; SURF-1; Surfeit locus protein 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SURF1. AA range:171-220
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 30kD
GeneID（Human）: 6834
Human Swiss-Prot No: Q15526
Cellular localization: Mitochondrion inner membrane ; Multi-pass membrane protein .
Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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