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ELK Biotechnology

ES3501

SSB Rabbit Polyclonal Antibody

SSB Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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SSB Rabbit Polyclonal Antibody

Overview

Product name: SSB rabbit pAb
Alternative Names: SSB; Lupus La protein; La autoantigen; La ribonucleoprotein; Sjoegren syndrome type B antigen; SS-B
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SSB. AA range:341-390
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 47kD
GeneID（Human）: 6741
Human Swiss-Prot No: P05455
Cellular localization: Nucleus .
Background: Sjogren syndrome antigen B(SSB) Homo sapiens The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014],
Species Reactivity: Human;Rat;Mouse;
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