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ELK Biotechnology
SKU:ES3478
SOD-1 Rabbit Polyclonal Antibody
SOD-1 Rabbit Polyclonal Antibody
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SOD-1 Rabbit Polyclonal Antibody
Overview
| Product name: | SOD-1 rabbit pAb |
| Alternative Names: | SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SOD-1. AA range:36-85 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 18kD |
| GeneID（Human）: | 6647 |
| Human Swiss-Prot No: | P00441 |
| Cellular localization: | Cytoplasm . Mitochondrion . Nucleus . Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. . |
| Background: | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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