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ELK Biotechnology

SKU:ES3443

Siah-2 Rabbit Polyclonal Antibody

Siah-2 Rabbit Polyclonal Antibody

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Siah-2 Rabbit Polyclonal Antibody

Overview

Product name: Siah-2 rabbit pAb
Alternative Names: SIAH2; E3 ubiquitin-protein ligase SIAH2; Seven in absentia homolog 2; Siah-2; hSiah2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SIAH2. AA range:241-290
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID(Human): 6478
Human Swiss-Prot No: O43255
Cellular localization: Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. .
Background: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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