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ELK Biotechnology
SKU:ES3420
SENP5 Rabbit Polyclonal Antibody
SENP5 Rabbit Polyclonal Antibody
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$248.00 USD
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SENP5 Rabbit Polyclonal Antibody
Overview
| Product name: | SENP5 rabbit pAb |
| Alternative Names: | SENP5; FKSG45; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 86kD |
| GeneID(Human): | 205564 |
| Human Swiss-Prot No: | Q96HI0 |
| Cellular localization: | Nucleus, nucleolus . |
| Background: | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009], |
| Species Reactivity: | Human;Mouse;Monkey |
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Western Blot analysis of various cells using SENP5 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SENP5 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from COS7 cells, using SENP5 Antibody. The lane on the right is blocked with the synthesized peptide.
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