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ELK Biotechnology
SKU:ES3413
Scn4b Rabbit Polyclonal Antibody
Scn4b Rabbit Polyclonal Antibody
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$248.00 USD
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Scn4b Rabbit Polyclonal Antibody
Overview
| Product name: | Scn4b rabbit pAb |
| Alternative Names: | SCN4B; Sodium channel subunit beta-4 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SCN4B. AA range:61-110 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 27kD |
| GeneID(Human): | 6330 |
| Human Swiss-Prot No: | Q8IWT1 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using Scn4b Polyclonal Antibody -
Western blot analysis of lysates from HepG2 and Jurkat cells, using SCN4B Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HeLa cells using SCN4B antibody. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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