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ELK Biotechnology
SKU:ES3389
RORα Rabbit Polyclonal Antibody
RORα Rabbit Polyclonal Antibody
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$248.00 USD
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RORα Rabbit Polyclonal Antibody
Overview
| Product name: | RORα rabbit pAb |
| Alternative Names: | RORA; NR1F1; RZRA; Nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; Retinoid-related orphan receptor-alpha |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RORA. AA range:6-55 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 60kD |
| GeneID(Human): | 6095 |
| Human Swiss-Prot No: | P35398 |
| Cellular localization: | Nucleus . |
| Background: | The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014], |
| Species Reactivity: | Human;Monkey |
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Western Blot analysis of various cells using RORα Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using RORA Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HeLa and COS7 cells, using RORA Antibody. The lane on the right is blocked with the synthesized peptide.
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