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ELK Biotechnology
SKU:ES3288
Rab 3 GAP p130 Rabbit Polyclonal Antibody
Rab 3 GAP p130 Rabbit Polyclonal Antibody
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$248.00 USD
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Rab 3 GAP p130 Rabbit Polyclonal Antibody
Overview
| Product name: | Rab 3 GAP p130 rabbit pAb |
| Alternative Names: | RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RAB3GAP1. AA range:538-587 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 117kD |
| GeneID(Human): | 22930 |
| Human Swiss-Prot No: | Q15042 |
| Cellular localization: | Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction. |
| Background: | This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using Rab 3 GAP p130 Polyclonal Antibody diluted at 1:2000 -
Immunohistochemistry analysis of paraffin-embedded human testis tissue, using RAB3GAP1 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from 293 cells, using RAB3GAP1 Antibody. The lane on the right is blocked with the synthesized peptide.
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