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ELK Biotechnology

SKU:ES3288

Rab 3 GAP p130 Rabbit Polyclonal Antibody

Rab 3 GAP p130 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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Rab 3 GAP p130 Rabbit Polyclonal Antibody

Overview

Product name: Rab 3 GAP p130 rabbit pAb
Alternative Names: RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RAB3GAP1. AA range:538-587
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 117kD
GeneID(Human): 22930
Human Swiss-Prot No: Q15042
Cellular localization: Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction.
Background: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010],
Species Reactivity: Human;Rat;Mouse;
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