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ELK Biotechnology

SKU:ES3284

PU.1 Rabbit Polyclonal Antibody

PU.1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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PU.1 Rabbit Polyclonal Antibody

Overview

Product name: PU.1 rabbit pAb
Alternative Names: SPI1; Transcription factor PU.1; 31 kDa-transforming protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SPI1. AA range:181-230
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 32kD
GeneID(Human): 6688
Human Swiss-Prot No: P17947
Cellular localization: Nucleus .
Background: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat;Monkey
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