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ELK Biotechnology
SKU:ES3270
PSMC6 Rabbit Polyclonal Antibody
PSMC6 Rabbit Polyclonal Antibody
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$248.00 USD
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PSMC6 Rabbit Polyclonal Antibody
Overview
| Product name: | PSMC6 rabbit pAb |
| Alternative Names: | PSMC6; SUG2; 26S protease regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42 |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PSMC6. AA range:61-110 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 44kD |
| GeneID(Human): | 5706 |
| Human Swiss-Prot No: | P62333 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | proteasome 26S subunit, ATPase 6(PSMC6) Homo sapiens The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chrom |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using PSMC6 Polyclonal Antibody -
Western blot analysis of lysates from HepG2, 293, and RAW264.7 cells, using PSMC6 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HeLa cells using PSMC6 antibody. -
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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