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ELK Biotechnology

ES3256

PRAF2 Rabbit Polyclonal Antibody

PRAF2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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PRAF2 Rabbit Polyclonal Antibody

Overview

Product name: PRAF2 rabbit pAb
Alternative Names: PRAF2; JM4; PRA1 family protein 2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human JM4. AA range:129-178
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 20kD
GeneID（Human）: 11230
Human Swiss-Prot No: O60831
Cellular localization: Endosome membrane ; Multi-pass membrane protein .
Background: function:May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.,similarity:Belongs to the PRA1 family.,subunit:Interacts with CCR5 and GDE1.,tissue specificity:Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.,
Species Reactivity: Human;Mouse;Rat
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