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ELK Biotechnology
SKU:ES3253
PPP2R3C Rabbit Polyclonal Antibody
PPP2R3C Rabbit Polyclonal Antibody
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$248.00 USD
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PPP2R3C Rabbit Polyclonal Antibody
Overview
| Product name: | PPP2R3C rabbit pAb |
| Alternative Names: | PPP2R3C; C14orf10; G5PR; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C |
| Applications: | WB;ELISA;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PPP2R3C. AA range:165-214 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 55012 |
| Human Swiss-Prot No: | Q969Q6 |
| Cellular localization: | Nucleus . Cytoplasm . Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis. . |
| Background: | This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using PPP2R3C Polyclonal Antibody -
Western blot analysis of PPP2R3C Antibody. The lane on the right is blocked with the PPP2R3C peptide. -
Western blot analysis of the lysates from HepG2 cells using PPP2R3C antibody. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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