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ELK Biotechnology

ES3245

POT1 Rabbit Polyclonal Antibody

POT1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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POT1 Rabbit Polyclonal Antibody

Overview

Product name: POT1 rabbit pAb
Alternative Names: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID（Human）: 25913
Human Swiss-Prot No: Q9NUX5
Cellular localization: Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA.
Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Monkey
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