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ELK Biotechnology
SKU:ES3240
PMS1 Rabbit Polyclonal Antibody
PMS1 Rabbit Polyclonal Antibody
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$248.00 USD
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PMS1 Rabbit Polyclonal Antibody
Overview
| Product name: | PMS1 rabbit pAb |
| Alternative Names: | PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PMS1. AA range:441-490 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 105kD |
| GeneID(Human): | 5378 |
| Human Swiss-Prot No: | P54277 |
| Cellular localization: | Nucleus . |
| Background: | This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using PMS1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Western Blot analysis of Jurkat cells using PMS1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i -
Immunohistochemistry analysis of paraffin-embedded human brain, using PMS1 Antibody. The picture on the right is blocked with the synthesized peptide.
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