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ELK Biotechnology
SKU:ES3203
PIAS 1 Rabbit Polyclonal Antibody
PIAS 1 Rabbit Polyclonal Antibody
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$248.00 USD
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PIAS 1 Rabbit Polyclonal Antibody
Overview
| Product name: | PIAS 1 rabbit pAb |
| Alternative Names: | PIAS1; DDXBP1; E3 SUMO-protein ligase PIAS1; DEAD/H box-binding protein 1; Gu-binding protein; GBP; Protein inhibitor of activated STAT protein 1; RNA helicase II-binding protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PIAS1. AA range:10-59 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 72kD |
| GeneID(Human): | 8554 |
| Human Swiss-Prot No: | O75925 |
| Cellular localization: | Nucleus speckle . Nucleus, PML body . Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton. |
| Background: | This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using PIAS 1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using PIAS1 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HUVEC cells, using PIAS1 Antibody. The lane on the right is blocked with the synthesized peptide.
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