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ELK Biotechnology

ES3183

PFK-2 liv Rabbit Polyclonal Antibody

PFK-2 liv Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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PFK-2 liv Rabbit Polyclonal Antibody

Overview

Product name: PFK-2 liv rabbit pAb
Alternative Names: PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PFKFB1. AA range:406-455
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 58kD
GeneID（Human）: 5207
Human Swiss-Prot No: P16118
Cellular localization: cytosol,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex,
Background: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],
Species Reactivity: Human;Mouse;Rat
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