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ELK Biotechnology
SKU:ES3162
PDE4B/C/D Rabbit Polyclonal Antibody
PDE4B/C/D Rabbit Polyclonal Antibody
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$248.00 USD
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PDE4B/C/D Rabbit Polyclonal Antibody
Overview
| Product name: | PDE4B/C/D rabbit pAb |
| Alternative Names: | PDE4B; DPDE4; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PDE4D. AA range:156-205 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 76kD |
| GeneID(Human): | 5144/5142/5143 |
| Human Swiss-Prot No: | Q07343/Q08493/Q08499 |
| Cellular localization: | [Isoform PDE4B5]: Cytoplasm . Cell membrane . |
| Background: | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using PDE4B/C/D Polyclonal Antibody -
Western Blot analysis of K562 cells using PDE4B/C/D Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using PDE4D Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from K562 cells, treated with H2O2 100uM 30', using PDE4D Antibody. The lane on the right is blocked with the synthesized peptide.
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