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ELK Biotechnology
SKU:ES3148
PAR-4 Rabbit Polyclonal Antibody
PAR-4 Rabbit Polyclonal Antibody
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PAR-4 Rabbit Polyclonal Antibody
Overview
| Product name: | PAR-4 rabbit pAb |
| Alternative Names: | F2RL3; PAR4; Proteinase-activated receptor 4; PAR-4; Coagulation factor II receptor-like 3; Thrombin receptor-like 3 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PAR4. AA range:29-78 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 41kD |
| GeneID(Human): | 9002 |
| Human Swiss-Prot No: | Q96RI0 |
| Cellular localization: | Cell membrane; Multi-pass membrane protein. |
| Background: | This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using PAR-4 Polyclonal Antibody -
Immunofluorescence analysis of LOVO cells, using PAR4 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HepG2 and Jurkat/HeLa cells, using PAR4 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HT-29 cells using PAR4 antibody.
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