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ELK Biotechnology
SKU:ES3144
PAI-3 Rabbit Polyclonal Antibody
PAI-3 Rabbit Polyclonal Antibody
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PAI-3 Rabbit Polyclonal Antibody
Overview
| Product name: | PAI-3 rabbit pAb |
| Alternative Names: | SERPINA5; PCI; PLANH3; Plasma serine protease inhibitor; Acrosomal serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Serpin A5. AA range:260-309 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 42kD |
| GeneID(Human): | 155698 |
| Human Swiss-Prot No: | P05154 |
| Cellular localization: | Secreted, extracellular space . Localized on the plasma membrane overlying the acrosomal head of spermatozoa of ependymal spermatozoa and ejaculated sperm. Localized at the equatorial segment of acrosome-reacted spematozoa. Localized in alpha granules in resting platelets and on the external plasma membrane and within the surface-connected cannalicular system in activated platelets. |
| Background: | The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using PAI-3 Polyclonal Antibody -
Western Blot analysis of Hela cells using PAI-3 Polyclonal Antibody -
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbe -
Western blot analysis of lysates from Jurkat cells, using Serpin A5 Antibody. The lane on the right is blocked with the synthesized peptide.
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