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ELK Biotechnology
SKU:ES2871
MyD88 Rabbit Polyclonal Antibody
MyD88 Rabbit Polyclonal Antibody
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$248.00 USD
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MyD88 Rabbit Polyclonal Antibody
Overview
| Product name: | MyD88 rabbit pAb |
| Alternative Names: | MYD88; Myeloid differentiation primary response protein MyD88 |
| Applications: | IF;WB;IHC;ELISA |
| Recommended Dilutions: | IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunocytochemistry: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 33kD |
| GeneID（Human）: | 4615 |
| Human Swiss-Prot No: | Q99836 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010], |
| Species Reactivity: | Human;Mouse;Rat;Pig |
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