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ELK Biotechnology

ES2870

MVK Rabbit Polyclonal Antibody

MVK Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MVK Rabbit Polyclonal Antibody

Overview

Product name: MVK rabbit pAb
Alternative Names: MVK; Mevalonate kinase; MK
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Mevalonate Kinase. AA range:151-200
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 42kD
GeneID（Human）: 4598
Human Swiss-Prot No: Q03426
Cellular localization: Cytoplasm . Peroxisome .
Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Species Reactivity: Human;Monkey
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