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ELK Biotechnology
SKU:ES2863
MTHFR Rabbit Polyclonal Antibody
MTHFR Rabbit Polyclonal Antibody
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$248.00 USD
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MTHFR Rabbit Polyclonal Antibody
Overview
| Product name: | MTHFR rabbit pAb |
| Alternative Names: | MTHFR; Methylenetetrahydrofolate reductase |
| Applications: | WB;ELISA;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 75kD |
| GeneID(Human): | 4524 |
| Human Swiss-Prot No: | P42898 |
| Cellular localization: | cytosol,synapse, |
| Background: | The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009], |
| Species Reactivity: | Human;Mouse;Monkey |
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Western Blot analysis of various cells using MTHFR Polyclonal Antibody -
Western blot analysis of lysate from COLO205 cells treated with Forskolin, using MTHFR antibody. -
Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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