MRE11 Rabbit Polyclonal Antibody

Name: MRE11 Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES2819
Price: 248.0 USD
Availability: InStock

$248.00 USD

Sale Sold out

Shipping calculated at checkout.

Size 100ul

Product variants

Quantity

MRE11 Rabbit Polyclonal Antibody

Overview

Product name:	MRE11 rabbit pAb
Alternative Names:	MRE11A; HNGS1; MRE11; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human MRE11. AA range:230-279
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	80kD
GeneID（Human）:	4361
Human Swiss-Prot No:	P49959
Cellular localization:	Nucleus . Chromosome, telomere . Chromosome . Localizes to discrete nuclear foci after treatment with genotoxic agents. .
Background:	This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity:	Human;Mouse;Rat;Monkey

Western Blot analysis of various cells using MRE11 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of COS7 cells using MRE11 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i
Western blot analysis of lysates from Jurkat cells, treated with UV 15', using MRE11 Antibody. The lane on the right is blocked with the synthesized peptide.

View full details

Country/region

MRE11 Rabbit Polyclonal Antibody

MRE11 Rabbit Polyclonal Antibody

Overview