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ELK Biotechnology

ES2803

MMP-11 Rabbit Polyclonal Antibody

MMP-11 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MMP-11 Rabbit Polyclonal Antibody

Overview

Product name: MMP-11 rabbit pAb
Alternative Names: MMP11; STMY3; Stromelysin-3; SL-3; ST3; Matrix metalloproteinase-11; MMP-11
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-11. AA range:61-110
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID（Human）: 4320
Human Swiss-Prot No: P24347
Cellular localization: Secreted, extracellular space, extracellular matrix .
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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