Skip to product information
1 of 1

ELK Biotechnology

SKU:ES2788

MGMT Rabbit Polyclonal Antibody

MGMT Rabbit Polyclonal Antibody

Regular price $248.00 USD
Regular price Sale price $248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

MGMT Rabbit Polyclonal Antibody

Overview

Product name: MGMT rabbit pAb
Alternative Names: MGMT; Methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 22kD
GeneID(Human): 4255
Human Swiss-Prot No: P16455
Cellular localization: Nucleus.
Background: Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015],
Species Reactivity: Human;Rat
View full details