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ELK Biotechnology
SKU:ES2778
Menin Rabbit Polyclonal Antibody
Menin Rabbit Polyclonal Antibody
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$248.00 USD
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Menin Rabbit Polyclonal Antibody
Overview
| Product name: | Menin rabbit pAb |
| Alternative Names: | MEN1; SCG2; Menin |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MEN1. AA range:181-230 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 67kD |
| GeneID(Human): | 4221 |
| Human Swiss-Prot No: | O00255 |
| Cellular localization: | Nucleus . Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation. |
| Background: | This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Menin Polyclonal Antibody diluted at 1:500 -
Western Blot analysis of HuvEc cells using Menin Polyclonal Antibody diluted at 1:500 -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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