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ELK Biotechnology
SKU:ES2766
MEF-2 Rabbit Polyclonal Antibody
MEF-2 Rabbit Polyclonal Antibody
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MEF-2 Rabbit Polyclonal Antibody
Overview
| Product name: | MEF-2 rabbit pAb |
| Alternative Names: | MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MEF2A. AA range:374-423 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 4205 |
| Human Swiss-Prot No: | Q02078 |
| Cellular localization: | Nucleus . |
| Background: | The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using MEF-2 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunofluorescence analysis of HeLa cells, using MEF2A Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MEF2A Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HeLa cells, treated with PMA 125ng/ml 30', using MEF2A Antibody. The lane on the right is blocked with the synthesized peptide.
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