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ELK Biotechnology

ES2757

MC2-R Rabbit Polyclonal Antibody

MC2-R Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MC2-R Rabbit Polyclonal Antibody

Overview

Product name: MC2-R rabbit pAb
Alternative Names: MC2R; ACTHR; Adrenocorticotropic hormone receptor; ACTH receptor; ACTH-R; Adrenocorticotropin receptor; Melanocortin receptor 2; MC2-R
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human ACTHR. AA range:248-297
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 34kD
GeneID（Human）: 4158
Human Swiss-Prot No: Q01718
Cellular localization: Cell membrane; Multi-pass membrane protein.
Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014],
Species Reactivity: Human;Mouse
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