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ELK Biotechnology
SKU:ES2732
LUCA15 Rabbit Polyclonal Antibody
LUCA15 Rabbit Polyclonal Antibody
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$248.00 USD
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LUCA15 Rabbit Polyclonal Antibody
Overview
| Product name: | LUCA15 rabbit pAb |
| Alternative Names: | RBM5; H37; LUCA15; RNA-binding protein 5; Protein G15; Putative tumor suppressor LUCA15; RNA-binding motif protein 5; Renal carcinoma antigen NY-REN-9 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RBM5. AA range:226-275 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 92kD |
| GeneID(Human): | 10181 |
| Human Swiss-Prot No: | P52756 |
| Cellular localization: | Nucleus . |
| Background: | This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using LUCA15 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using RBM5 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HUVEC cells, using RBM5 Antibody. The lane on the right is blocked with the synthesized peptide.
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