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ELK Biotechnology
SKU:ES2726
LRRC41 Rabbit Polyclonal Antibody
LRRC41 Rabbit Polyclonal Antibody
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$248.00 USD
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LRRC41 Rabbit Polyclonal Antibody
Overview
| Product name: | LRRC41 rabbit pAb |
| Alternative Names: | LRRC41; MUF1; PP7759; Leucine-rich repeat-containing protein 41; Protein Muf1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 80kD |
| GeneID(Human): | 10489 |
| Human Swiss-Prot No: | Q15345 |
| Cellular localization: | nucleus,cytoplasm,membrane, |
| Background: | caution:It is uncertain whether Met-1 or Met-23 is the initiator.,domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].,function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2., |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using LRRC41 Polyclonal Antibody -
Western Blot analysis of K562 cells using LRRC41 Polyclonal Antibody -
Western blot analysis of lysates from rat kidney and rat heart cells, using LRRC41 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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