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ELK Biotechnology

ES2724

LRAT Rabbit Polyclonal Antibody

LRAT Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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LRAT Rabbit Polyclonal Antibody

Overview

Product name: LRAT rabbit pAb
Alternative Names: LRAT; Lecithin retinol acyltransferase; Phosphatidylcholine--retinol O-acyltransferase
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human LRAT. AA range:111-160
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 27kD
GeneID（Human）: 9227
Human Swiss-Prot No: O95237
Cellular localization: Endoplasmic reticulum membrane ; Single-pass membrane protein . Rough endoplasmic reticulum . Endosome, multivesicular body . Cytoplasm, perinuclear region . Present in the rough endoplasmic reticulum and multivesicular body in hepatic stellate cells. Present in the rough endoplasmic reticulum and perinuclear region in endothelial cells (By similarity). .
Background: lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)(LRAT) Homo sapiens The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],
Species Reactivity: Human;Mouse;Rat
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