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ELK Biotechnology

ES2702

LAT Rabbit Polyclonal Antibody

LAT Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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LAT Rabbit Polyclonal Antibody

Overview

Product name: LAT rabbit pAb
Alternative Names: LAT; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human LAT. AA range:171-220
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID（Human）: 27040
Human Swiss-Prot No: O43561
Cellular localization: Cell membrane ; Single-pass type III membrane protein . Present in lipid rafts.
Background: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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