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ELK Biotechnology
SKU:ES2673
Ki-67 Rabbit Polyclonal Antibody
Ki-67 Rabbit Polyclonal Antibody
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Ki-67 Rabbit Polyclonal Antibody
Overview
| Product name: | Ki-67 rabbit pAb |
| Alternative Names: | MKI67; Antigen KI-67 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Ki67. AA range:3207-3256 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 360kD |
| GeneID（Human）: | 4288 |
| Human Swiss-Prot No: | P46013 |
| Cellular localization: | Chromosome . Nucleus . Nucleus, nucleolus . Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface (PubMed:27362226). Associates with satellite DNA in G1 phase (PubMed:9510506). Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes (PubMed:15896774, PubMed:22002106). Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix (PubMed:22002106). . |
| Background: | This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009], |
| Species Reactivity: | Human;Rat;Mouse; |
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