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ELK Biotechnology
SKU:ES2635
IP3KA Rabbit Polyclonal Antibody
IP3KA Rabbit Polyclonal Antibody
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$248.00 USD
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IP3KA Rabbit Polyclonal Antibody
Overview
| Product name: | IP3KA rabbit pAb |
| Alternative Names: | ITPKA; Inositol-trisphosphate 3-kinase A; Inositol 1; 4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A |
| Applications: | WB;ELISA;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human IP3KA. AA range:396-445 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 52kD |
| GeneID(Human): | 3706 |
| Human Swiss-Prot No: | P23677 |
| Cellular localization: | Cytoplasm, cytoskeleton . |
| Background: | Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using IP3KA Polyclonal Antibody -
Western blot analysis of lysates from HUVEC cells, using IP3KA Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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