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ELK Biotechnology
SKU:ES2600
IKKα Rabbit Polyclonal Antibody
IKKα Rabbit Polyclonal Antibody
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$248.00 USD
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IKKα Rabbit Polyclonal Antibody
Overview
| Product name: | IKKα rabbit pAb |
| Alternative Names: | CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human IKK-alpha. AA range:15-64 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 85kD |
| GeneID(Human): | 1147 |
| Human Swiss-Prot No: | O15111 |
| Cellular localization: | Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus. |
| Background: | This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using IKKα Polyclonal Antibody diluted at 1:1000 -
Western Blot analysis of 293 cells using IKKα Polyclonal Antibody diluted at 1:1000 -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using IKK-alpha Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from 293 cells, treated with EGF, using IKK-alpha Antibody. The lane on the right is blocked with the synthesized peptide.
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