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ELK Biotechnology
SKU:ES2596
IGFBP3 Rabbit Polyclonal Antibody
IGFBP3 Rabbit Polyclonal Antibody
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$248.00 USD
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IGFBP3 Rabbit Polyclonal Antibody
Overview
| Product name: | IGFBP3 rabbit pAb |
| Alternative Names: | IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human IGFBP-3. AA range:151-200 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 31kD |
| GeneID(Human): | 3486 |
| Human Swiss-Prot No: | P17936 |
| Cellular localization: | Secreted . |
| Background: | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using IGFBP3 Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Western Blot analysis of MOUSE-BRAIN cells using IGFBP3 Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using IGFBP-3 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from RAW246.7 cells, using IGFBP-3 Antibody. The lane on the right is blocked with the synthesized peptide.
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