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ELK Biotechnology

ES2540

HMG-2 Rabbit Polyclonal Antibody

HMG-2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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HMG-2 Rabbit Polyclonal Antibody

Overview

Product name: HMG-2 rabbit pAb
Alternative Names: HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human HMGB2. AA range:131-180
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 27kD
GeneID（Human）: 3148
Human Swiss-Prot No: P26583
Cellular localization: Nucleus . Chromosome . Cytoplasm . Secreted . In basal state predominantly nuclear. .
Background: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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