Histone H2B Rabbit Polyclonal Antibody

Name: Histone H2B Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES2527
Price: 248.0 USD
Availability: InStock

$248.00 USD

Sale Sold out

Shipping calculated at checkout.

Size 100ul

Product variants

Quantity

Histone H2B Rabbit Polyclonal Antibody

Overview

Product name:	Histone H2B rabbit pAb
Alternative Names:	H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:10-59
Storage:	-20°C/1 year
Storage:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	14kD
GeneID（Human）:	54145
Human Swiss-Prot No:	P57053
Cellular localization:	Nucleus. Chromosome.
Background:	H2BFS is a Pseudogene. Histone H2B type 1-H is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. Diseases associated with H2BFS include endometrial stromal sarcoma. Among its related pathways are Packaging Of Telomere Ends. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BH.
Species Reactivity:	Human;Mouse;Monkey

Western Blot analysis of various cells using Histone H2B Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of COS7 cells using Histone H2B Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunofluorescence analysis of HeLa cells, using Histone H2B Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Histone H2B Antibody. The picture on the right is blocked with the synthesized peptide.

View full details

Country/region

Histone H2B Rabbit Polyclonal Antibody

Histone H2B Rabbit Polyclonal Antibody

Overview