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ELK Biotechnology
SKU:ES2518
Histone deacetylase 1 Rabbit Polyclonal Antibody
Histone deacetylase 1 Rabbit Polyclonal Antibody
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$248.00 USD
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Histone deacetylase 1 Rabbit Polyclonal Antibody
Overview
| Product name: | Histone deacetylase 1 rabbit pAb |
| Alternative Names: | HDAC1; RPD3L1; Histone deacetylase 1; HD1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human HDAC1. AA range:433-482 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 3065 |
| Human Swiss-Prot No: | Q13547 |
| Cellular localization: | Nucleus . |
| Background: | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Histone deacetylase 1 Polyclonal Antibody diluted at 1:1000 -
Western Blot analysis of hela cells using Histone deacetylase 1 Polyclonal Antibody diluted at 1:1000 -
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbe -
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbe
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