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ELK Biotechnology
SKU:ES2504
HDAC6 Rabbit Polyclonal Antibody
HDAC6 Rabbit Polyclonal Antibody
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$248.00 USD
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HDAC6 Rabbit Polyclonal Antibody
Overview
| Product name: | HDAC6 rabbit pAb |
| Alternative Names: | HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human HDAC6. AA range:7-56 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 131kD |
| GeneID(Human): | 10013 |
| Human Swiss-Prot No: | Q9UBN7 |
| Cellular localization: | Cytoplasm . Cytoplasm, cytoskeleton . Nucleus . Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules. . |
| Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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Immunofluorescence analysis of Hela cell. 1,HDAC6 Polyclonal Antibody(red) was diluted at 1:200(4° overnight). GFAP Monoclonal Antibody(5C8)(green) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 594 Catalog:RS3611 was diluted at 1:100 -
Western Blot analysis of various cells using HDAC6 Polyclonal Antibody diluted at 1:1000 -
Immunofluorescence analysis of HepG2 cells, using HDAC6 Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using HDAC6 Antibody. The picture on the right is blocked with the synthesized peptide.
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