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ELK Biotechnology
SKU:ES2499
HDAC2 Rabbit Polyclonal Antibody
HDAC2 Rabbit Polyclonal Antibody
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$248.00 USD
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HDAC2 Rabbit Polyclonal Antibody
Overview
| Product name: | HDAC2 rabbit pAb |
| Alternative Names: | HDAC2; Histone deacetylase 2; HD2 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human HDAC2. AA range:360-409 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 3066 |
| Human Swiss-Prot No: | Q92769 |
| Cellular localization: | Nucleus . Cytoplasm . |
| Background: | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010], |
| Species Reactivity: | Human;Mouse;Rat;Monkey |
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Western Blot analysis of various cells using HDAC2 Polyclonal Antibody diluted at 1:2000 -
Western Blot analysis of HepG2 cells using HDAC2 Polyclonal Antibody diluted at 1:2000 -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HDAC2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HepG2 cells, using HDAC2 Antibody. The lane on the right is blocked with the synthesized peptide.
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