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ELK Biotechnology

SKU:ES2495

HBP1 Rabbit Polyclonal Antibody

HBP1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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HBP1 Rabbit Polyclonal Antibody

Overview

Product name: HBP1 rabbit pAb
Alternative Names: HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human HBP1. AA range:431-480
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID(Human): 26959
Human Swiss-Prot No: O60381
Cellular localization: Nucleus .
Background: function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,
Species Reactivity: Human;Mouse;Rat;Monkey
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