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ELK Biotechnology
SKU:ES2487
GSK3β Rabbit Polyclonal Antibody
GSK3β Rabbit Polyclonal Antibody
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$248.00 USD
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GSK3β Rabbit Polyclonal Antibody
Overview
| Product name: | GSK3β rabbit pAb |
| Alternative Names: | GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Applications: | IF;WB;IHC;IP;ELISA |
| Recommended Dilutions: | IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GSK3B. AA range:1-50 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 47kD |
| GeneID（Human）: | 2932 |
| Human Swiss-Prot No: | P49841 |
| Cellular localization: | Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). . |
| Background: | The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009], |
| Species Reactivity: | Human;Mouse;Rat;Rabbit |
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