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ELK Biotechnology
SKU:ES2486
GSK3α/β Rabbit Polyclonal Antibody
GSK3α/β Rabbit Polyclonal Antibody
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$248.00 USD
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GSK3α/β Rabbit Polyclonal Antibody
Overview
| Product name: | GSK3α/β rabbit pAb |
| Alternative Names: | GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GSK3 alpha/beta. AA range:246-295 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 51,46kD |
| GeneID(Human): | 2931 |
| Human Swiss-Prot No: | P49840/P49841 |
| Cellular localization: | mitochondrion,cytosol,beta-catenin destruction complex,postsynapse, |
| Background: | glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011], |
| Species Reactivity: | Human;Mouse;Rat;Drosophila;Drosophila |
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Western Blot analysis of various cells using GSK3α/β Polyclonal Antibody diluted at 1:1000 -
Western Blot analysis of 293 cells using GSK3α/β Polyclonal Antibody diluted at 1:1000 -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using GSK3 alpha/beta Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from 293 cells, treated with TNF-a 20ng/ml 30', using GSK3 alpha/beta Antibody. The lane on the right is blocked with the synthesized peptide.
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