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ELK Biotechnology

ES2484

GSC2 Rabbit Polyclonal Antibody

GSC2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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GSC2 Rabbit Polyclonal Antibody

Overview

Product name: GSC2 rabbit pAb
Alternative Names: GSC2; GSCL; Homeobox protein goosecoid-2; GSC-2; Homeobox protein goosecoid-like; GSC-L
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GSC2. AA range:131-180
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 25kD
GeneID（Human）: 2928
Human Swiss-Prot No: O15499
Cellular localization: Nucleus .
Background: Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse
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