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ELK Biotechnology

SKU:ES2479

GRK 3 Rabbit Polyclonal Antibody

GRK 3 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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GRK 3 Rabbit Polyclonal Antibody

Overview

Product name: GRK 3 rabbit pAb
Alternative Names: ADRBK2; BARK2; GRK3; Beta-adrenergic receptor kinase 2; Beta-ARK-2; G-protein-coupled receptor kinase 3
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GRK3. AA range:361-410
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 80kD
GeneID(Human): 157
Human Swiss-Prot No: P35626
Cellular localization: Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .
Background: The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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