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ELK Biotechnology
SKU:ES2470
Granzyme K Rabbit Polyclonal Antibody
Granzyme K Rabbit Polyclonal Antibody
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$248.00 USD
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Granzyme K Rabbit Polyclonal Antibody
Overview
| Product name: | Granzyme K rabbit pAb |
| Alternative Names: | GZMK; TRYP2; Granzyme K; Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 33kD |
| GeneID(Human): | 3003 |
| Human Swiss-Prot No: | P49863 |
| Cellular localization: | Secreted. Cytoplasmic granule. |
| Background: | This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Granzyme K Polyclonal Antibody diluted at 1:1000 -
Immunofluorescence analysis of NIH/3T3 cells, using GRAK Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using GRAK Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from Jurkat cells, using GRAK Antibody. The lane on the right is blocked with the synthesized peptide.
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