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ELK Biotechnology

ES2425

GIPR Rabbit Polyclonal Antibody

GIPR Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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GIPR Rabbit Polyclonal Antibody

Overview

Product name: GIPR rabbit pAb
Alternative Names: GIPR; Gastric inhibitory polypeptide receptor; GIP-R; Glucose-dependent insulinotropic polypeptide receptor
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GIPR. AA range:93-142
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 53kD
GeneID（Human）: 2696
Human Swiss-Prot No: P48546
Cellular localization: Cell membrane; Multi-pass membrane protein.
Background: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011],
Species Reactivity: Human;Rat;Mouse;
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