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ELK Biotechnology

ES2415

GCSm-γ Rabbit Polyclonal Antibody

GCSm-γ Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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GCSm-γ Rabbit Polyclonal Antibody

Overview

Product name: GCSm-γ rabbit pAb
Alternative Names: GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GCSm-gamma. AA range:42-91
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 31kD
GeneID（Human）: 2730
Human Swiss-Prot No: P48507
Cellular localization: cytosol,glutamate-cysteine ligase complex,
Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
Species Reactivity: Human;Mouse;Rat;Monkey
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