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ELK Biotechnology

ES2411

GCP4 Rabbit Polyclonal Antibody

GCP4 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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GCP4 Rabbit Polyclonal Antibody

Overview

Product name: GCP4 rabbit pAb
Alternative Names: TUBGCP4; 76P; GCP4; Gamma-tubulin complex component 4; GCP-4; hGCP4; Gamma-ring complex protein 76 kDa; h76p; hGrip76
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TUBGCP4. AA range:191-240
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 76kD
GeneID（Human）: 27229
Human Swiss-Prot No: Q9UGJ1
Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Background: This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015],
Species Reactivity: Human;Mouse
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